Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions

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Structure and stability of 2S albumin-type peanut allergens: implications for the severity of peanut allergic reactions.

Resistance to proteolytic enzymes and heat is thought to be a prerequisite property of food allergens. Allergens from peanut (Arachis hypogaea) are the most frequent cause of fatal food allergic reactions. The allergenic 2S albumin Ara h 2 and the homologous minor allergen Ara h 6 were studied at the molecular level with regard to allergenic potency of native and protease-treated allergen. A hi...

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Response to major peanut and peach allergens in a population of children allergic to peanut

Response to major peanut and peach allergens in a population of children allergic to peanut. Garcia-Blanca A1, Gomez F2, Aranda A3, Blanca-Lopez N1, Mayorga C3, Torres2 MJ, Diaz-Perales A4, Blanca M2, Canto G1. 3Research Laboratory, Carlos Haya Hospital-FIMABIS, Málaga, Spain, 2Allergy Service, Carlos Haya Hospital, Málaga, Spain, 4Plant Biotechnology Institute (UPMINIA), Madrid, Spain,1Allergy...

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Evaluation of IgE antibodies to recombinant peanut allergens in patients with reported reactions to peanut.

BACKGROUND Peanut may cause severe reactions in allergic individuals. The objective was to evaluate IgE antibodies to various recombinant (r) peanut and birch pollen allergens in relation to IgE levels to whole peanut extract and severe allergic reactions to peanut. METHODS Seventy-four Swedish peanut-allergic patients (age: 14-61 years) reported previous peanut exposure and associated sympto...

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Cross-Reactivity of Peanut Allergens

Peanut seeds are currently widely used as source of human food ingredients in the United States of America and in European countries due to their high quality protein and oil content. This article describes the classification and molecular biology of peanut seed allergens with particular reference to their cross-reactivities. Currently, the IUIS allergen nomenclature subcommittee accepts 12 pea...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 2006

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj20051728